Butyrate is a short-chain fatty acid (SCFA) produced by gut microbiota during the fermentation of dietary fibres. It is a vital energy source for the cells that line the gut and plays an essential role in gut to microbiota balance.

Tributyrin is an oil-like form of butyrate containing three butyrate molecules as a triglyceride.

Tributyrin has been shown to have superior efficacy and bioavailability compared to butyrate salts.

Tributyrin has some organoleptic advantages over butyrate salts. It has no pungent smell compared to Butyrate salts, which makes it more pleasant to consume. Additionally, it has a higher purity than butyrate salts, making it a more concentrated source of butyrate.

Tributyrin can be put as a pure ingredient into a softgel without adding bulking agents, additives, colourants, additives or flavours like solid butyrate salts.

Tributyrin has higher bioavailability and is more stable than butyrate salts in the gut, allowing for the sustained release of butyrate over a longer period. This sustained release enhances the effects and reaches of butyrate on gut microbiota modulation.

Tight junctions are specialized protein structures that help keep the cells in the lining of the intestines tightly bound together, which helps prevent unwanted substances from leaking into the body. They act like a gatekeeper that allows nutrients to pass through, while keeping out harmful toxins and bacteria. When the tight junctions are damaged, it can lead to a condition called "leaky gut," which can contribute to various health issues.

Butyrate promotes the expression of tight junction proteins, such as claudins and occludins, which help to maintain the integrity of the gut lining. It also inhibits the expression of pro-inflammatory cytokines that can damage the gut lining and increase gut permeability. These actions contribute to the preservation of gut barrier function and help to prevent the translocation of harmful substances from the gut lumen into the bloodstream.

Butyrate has been shown to stimulate mucus production in the gut, providing a protective layer that shields the gut lining from luminal contents and pathogenic bacteria. This mechanism helps to maintain a balanced gut environment and prevent the colonization of pathogens in the gut.

Vitamin D is a fat-soluble vitamin that is essential for strong bones,
muscle function, and overall health. It is a fat-soluble vitamin that can be
obtained from certain foods or produced in the skin when exposed to sunlight.

It is called a hormone-like compound because it acts as a hormone in the
body by regulating various physiological functions, including calcium and
phosphorus metabolism, bone health, and immune system function.

There are two main types of Vitamin D: Vitamin D2 (ergocalciferol) and
Vitamin D3 (cholecalciferol). Vitamin D2 is primarily found in plant sources,
while Vitamin D3 is synthesized in the skin when exposed to sunlight and can
also be found in animal-based foods.

Vitamin D is crucial in maintaining bone health by promoting calcium absorption and mineralisation. Without adequate Vitamin D, the body cannot absorb enough calcium from the diet to maintain healthy bones, leading to conditions like osteoporosis.

Vitamin D is believed to play a crucial role in immune system function by
helping to regulate the activity of immune cells. It has been shown to help
increase the production of antimicrobial proteins, enhance the activity of
immune cells like T cells and B cells, and reduce inflammation. This is why
Vitamin D is often touted as an important nutrient for protecting against
infections and supporting overall immune system health.

VDRs are receptors found on many cells throughout the body that can bind with active Vitamin D (calcitriol) to regulate gene expression. When calcitriol binds to VDRs, it can turn on or off various genes that affect immune function, cell growth, and other physiological processes. Butyrate, a short-chain fatty acid produced by gut bacteria has been shown to enhance the expression of VDRs in the gut, which may increase the body's ability to absorb and utilize Vitamin D. Additionally, butyrate can also enhance the conversion of Vitamin D to its active form, calcitriol, which may further support immune system and bone health.

Recent research suggests that Vitamin D may act as a modulator of the microbiota in the upper GI tract.

AmpBiotic® is a breakthrough dietary supplement developed by RedoxBox® that combines Vitamin D3 and butyrate to support gut mucosal immunity through Vitamin D Receptors (VDR). VDRs are switches that regulate gene transcription, selectively determining which genes are expressed in a cell. Vitamin D/VDR regulates genes related to immunity and normal cell division.

The exciting part is that published scientific evidence consistently reports that butyrate helps express more VDRs in the cell and enhances Vitamin D3 binding ability. When combined, the effects of Vitamin D3 and butyrate in AmpBiotic® are not additive but exponential, making it a unique and innovative product that supports overall health and well-being.

TauBiotic® stands out as a superior butyrate supplement because of its unique features. Unlike other butyrate supplements that may have an unpleasant odour, TauBiotic® is a gastro-resistant softgel containing pure tributyrin, the most concentrated and bioavailable form of butyrate. Moreover, the gastro-resistant softgel is designed to release the butyrate in the appropriate site in the gastrointestinal (GI) tract, where it can be most effective. The site of release of butyrate in the GI tract is crucial for the supplement's effectiveness, and TauBiotic's PDRCap technology ensures that the butyrate is released in the right location. The enteric release softgels are based on a natural pectin-based material that does not rely on harmful chemical plasticisers to attain gastro-resistance. With TauBiotic®, you can enjoy the benefits of butyrate supplementation without the unpleasant odour or concerns about the effectiveness of the supplement.

We understand your concerns about the small amount of sorbitol present in our butyrate softgel capsules. We would like to assure you that the amount of sorbitol used in our product is very small and has been carefully selected to ensure that the softgels are gastro-resistant and long-lasting. The sorbitol we use is a type of sugar alcohol that is commonly found in many fruits and vegetables and is widely used in the food industry as a natural sweetener.

We also understand that some people sometimes need to follow a low FODMAP diet, which restricts the consumption of certain types of carbohydrates, including sorbitol.

However, the amount of sorbitol in our product is very small and is unlikely to cause any adverse effects, even for those following a low FODMAP diet.

Despite some initial concerns, the positive effects of butyrate on the gut microbiota can help with the objective of these types of restrictive diets. It's, in fact, a positive addition to FODMAP diets, which aim to improve gut barrier function, reduce low-grade inflammation, and restore a balanced functioning and diverse bacterial population.

The sorbitol used in our product is derived from either potato starch or corn starch, and in the case of corn, we can assure that it is not GMO. Our product constantly tests negative for gluten, indicating that possible allergens coming from the sorbitol we use are minimal or non-existent.

Yes, RedoxBox® follows Current Good Manufacturing Practices in Manufacturing, Packaging & Labeling Operations for Dietary Supplements. Only by adhering to GMP guidelines, we can assure the consumer ultra-pure products.

Yes. None of the products manufactured by RedoxBox® contain any materials that are derived from GMO crops.

RedoxBox sources raw materials that are gluten and dairy free. We manufacture in a cGMP certified facility, which practices all allergen control protocols.

Each batch of RedoxBox's finished product is specifically tested by third parties to certify that it is gluten and lactose free.

The term "organic" relates to foods that are grown following an  "integrated farming system that strives for sustainability, the enhancement of soil fertility and biological diversity whilst, with rare exceptions, prohibiting synthetic pesticides, antibiotics, synthetic fertilizers, genetically modified organisms, and growth hormones". Food grown following this system conveys a perception of quality to consumers. But it actually relates to foods that are grown rather than products that are formulated.

Many of our scientifically validated raw materials are not produced organically as they are synthesized. Our quality assurance program includes rigorous testing and scrupulous processing. The objective is ultra-high purity, be it with raw materials and finished products.

Unfortunately, our products are no longer vegan. It was a hard decision for us. If we wanted to improve the gastro-resistance of our capsules and extend its freshness we had no other option but to rely on bovine gelatin.

The current state of the art for vegan gelatin soft gels is just not there: they are not gastro-resistant and have reported issues regarding stability, increased porosity, and degradability. 

However, we remain committed and will do the transition as soon as technology for vegan softgels matures. We hope this technology leap is achieved in the shortest time possible!

Yes we do. RedoxBox® follows strict GMP guidelines to control the purity of its products and control possible contaminants, be it heavy metals or microbiological contamination. All in-house test and third-party test show absence or levels well below the trace thresholds we admit.

We currently deliver our products to 28 countries/territories in Europe. We ship to the UK and the 27 European Union members.

All UK orders ship domestically. All EU orders ship from within the EU.

No, all EU orders are shipped from within the EU. No import-export hassle or fees!

Unfortunately, not for the moment. Shipping to countries outside the UK & the EU implies that shipments are subject to export-import clearance and might be locally regulated. We can't always assure that the parcel will reach its final destination. If you still want to proceed with a shipment to your country, please send us an email to customer.care [at] redoxbox.com and we will make sure we look into it and prepare a personalized quote.

We use all major carriers, and local courier partners. You’ll be asked to select a delivery method during checkout.

Yes, we do! If you have questions or concerns, just drop us a line at customer.care [at] redoxbox.com and a friendly customer rep will get back to you asap.

We want to make sure you are happy with your purchases. To facilitate this goal, we have adopted a simple, liberal, no questions asked, 30-day return policy. For further information, please read our B2C (business to consumer)  Refund Policy.

All returns stay within its region: UK orders are returned to a UK address; all EU orders are returned to a EU address.

At RedoxBox® we understand that everyone is unique, and sometimes your microbiota will not play along. This is why we offer a 30-day money back guarantee: if you are not 100% happy with our product, we will refund it within 30 days. Check our refund policy to know more.

We currently accept payments in GBP (£ ) or EUROS (€). Prices are set accordingly when the checkout process starts. All shipments to the Euro zone are set in Euros. All other destinations are set in pound sterling.

Yes we currently accept Express Checkouts including Amazon®, Apple®, Google® & Shopify® Pay in our store. Make sure to go to the Cart/Basket to choose that payment option in the cart or during check-out.

Yes, we offer deep discounted or even free of charge product for research purposes. If you are a researcher specialized in the field of microbiota, gut and gut-brain axis, and you are in need of a high-quality butyrate dietary supplement, please apply here. We consider each application on the case by case basis.

It all depends on the type of research you are planning and designing. We study each case as per case basis and work together to reach an understanding. Be sure to fill the form with some basic details or contact us directly by email.

Yes, we welcome all inquiries, be it a small privately owned Vitamin Shop or a wholesale distributor. Our vision is to bring our products to as many consumers as possible, so that they can benefit from our innovations. Feel free to fill out this form.

Yes, we currently offer our products directly to consumers in the EU. We like to give consumers all possible choices. There are consumers that prefer the proximity and warmth of traditional Brick and Mortar Vitamin Shops or Health Stores, while others like the convenience of online ordering. At RedoxBox® we make sure our products can be present in all channels.

RedoxBox® has a commitment to privacy for its customers. We use several different order and question forms to gather information on our website. All replies are transmitted over secure lines that cannot be accessed or read by anyone else on the Internet. RedoxBox's site uses SSL encryption certificate from Shopify. For more detailed information on this subject, please refer to our Privacy Policy.

RedoxBox® has made a big effort to be as GDPR (EU General Data Protection Regulation) compliant as possible (believe us! it is not easy to navigate this piece of legislation). You will notice that we explicitly seek your approval to gather information, whether it's filling a form, placing an order or just browsing the site. We obviously need some data to offer you a functional website and walk you through the order process, but be sure that we are not data-hunters or gatherers. We are not in the data business. All in all, please make sure to review our privacy and cookie policy.

You may initiate the procedure sending an email to us at customer.care [at] redoxbox.com (you need to have an account). Once we recieve your request we will process and send all the data we currently hold about you and you will be able to act upon it. You may even anonymize your orders, although for accounting/tax purposes we need to keep a minimum record of the transactions.